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High-dose radiation can be effective in reducing the size of the tumor and alleviating symptoms, though it may not always result in a cure

has received honoraria for lectures/advisory boards and research support from Astra Zeneca, Boehringer Ingelheim, Pharmaserve Lilly, Sanofi-Aventis, ELPEN, MSD, and Novo Nordisk

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In addition, it needs to be established whether the differential toxicity observed in liver slices can be reproduced using isolated hepatocytes, or in other in vitro models

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